发明名称 Aza-amino acid derivatives (factor Xa inhibitors 15)
摘要 The invention relates to semicarbazides of the general formula Iwhere R<1>, R<2>, R<3>, R<4 >and I have the meaning indicated in claim 1.The compounds of the formula I can be employed as pharmaceutical active compounds in human and veterinary medicine, in particular for the control and prevention of thromboembolic disorders such as thrombosis, mycocardial infarct, arteriosclerosis, inflammation, apoplexy, angina pectoris, restenosis after angioplasty and intermittent claudication.
申请公布号 US6849626(B2) 申请公布日期 2005.02.01
申请号 US20030362050 申请日期 2003.08.04
申请人 MERCK PATENT GMBH 发明人 MEDERSKI WERNER;JURASZYK HORST;DORSCH DIETER;TSAKLAKIDIS CHRISTOS;GLEILTZ JOHANNES;BARNES CHRISTOPHER
分类号 C07D295/08;A61K31/175;A61K31/357;A61K31/41;A61K31/4409;A61K31/445;A61K31/5375;A61P7/02;A61P9/00;A61P9/10;A61P29/00;A61P35/00;C07C311/16;C07C311/47;C07C317/26;C07C317/42;C07C333/04;C07D211/44;C07D211/46;C07D213/30;C07D257/04;C07D295/088;C07D317/34;C07D317/40;(IPC1-7):A61K31/175;A61K31/18 主分类号 C07D295/08
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