| 发明名称 |
VACINA DE HERPESVIRUS DEFICIENTE NA MORFOGENESE |
| 摘要 |
<p>A vaccine is described which comprises an assembly-deficient herpesvirus. The mutant herpesvirus is capable of infecting and undergoing DNA replication in the cells of a susceptible mammal, but is defective in capsid assembly and formation of mature virion particles. The assembly-deficient herpesvirus is avirulent and capable of generating a protective immune response in a vaccinated mammal.</p> |
| 申请公布号 |
PT956045(E) |
申请公布日期 |
2005.01.31 |
| 申请号 |
PT19970937214T |
申请日期 |
1997.07.25 |
| 申请人 |
G. D. SEARLE & CO. |
发明人 |
HIPPENMEYER, PAUL, J.;RANKIN, ANNE, M.;LUCKOW, VERNE, A. |
| 分类号 |
C12N15/09;A61K38/46;A61K39/00;A61K39/245;A61K48/00;A61P31/22;C12N5/10;C12N7/00;C12N9/50;C12N15/52;C12R1/92;(IPC1-7):A61K39/245 |
主分类号 |
C12N15/09 |
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