| 发明名称 |
Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament |
| 摘要 |
A crystalline monohydrate of (1á, 2â, 4â, 5á, 7â)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-bromide (tiotropium bromide monohydrate). A process for the production of the abovementioned compound is also disclosed and pharmaceutical compounds having an anticholinergic activity, suitable for the treatment of COPD and asthma. |
| 申请公布号 |
NZ525733(A) |
申请公布日期 |
2005.01.28 |
| 申请号 |
NZ20010525733 |
申请日期 |
2001.09.28 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO |
发明人 |
BANHOLZER, ROLF;SIEGER, PETER;KULINNA, CHRISTIAN;TRUNK, MICHAEL;GRAULICH, MANFRED;SPECHT, PETER;MEISSNER, HELMUT;MATHES, ANDREAS |
| 分类号 |
A61K9/14;A61K9/72;A61K31/439;A61K31/46;A61P11/00;A61P11/06;A61P43/00;C07D451/10;C07D451/14;(IPC1-7):C07D451/10 |
主分类号 |
A61K9/14 |
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