СПОСОБ ЭКСПРЕСС-КОНТРОЛЯ АНТИБИОТИКОЧУВСТВИТЕЛЬНОСТИ У БОЛЬНЫХ ХЛАМИДИОЗОМ, МИКОПЛАЗМОЗОМ И УРЕАПЛАЗМОЗОМ

摘要

FIELD: medicine, microbiology. ^ SUBSTANCE: method involves preparing smears from clinical material taken in inspected patients and carrying out analysis for the presence chlamydia, mycoplasma and ureaplasma in smears by method of fluorescent antibodies. The total amount of cells damaged by these pathogens is determined. In 2-7 days from the treatment onset smears are taken again and analysis of clinical material is repeated by the same method. The high sensitivity to antibiotic in this microorganism is estimated in detection <5% of epithelial cells in smear containing bright-green granules of the corresponding agent, and the prescribed treatment course with the same antibiotic is continued. The low sensitivity to antibiotic is estimated in detection >=5% of above indicated specifically luminescent granules of antigen, and in this case a medicinal preparation is replaced. Method provides carrying out determining the effectiveness of antibiotics effect for the first days after their prescription and to correct their prescription operatively. Method is simple and doesn't require the preliminary isolation of the pathogen culture. ^ EFFECT: improved method for express-control. ^ 5 ex