USE OF DAPSONE AS A NEUROPROTECTOR IN THE BRAIN STROKE

摘要

The invention relates to the use of dapsone as the first effective treatment against the disabling consequences associated with cerebral infarction in patients. Dapsone was evaluated as a neuroprotector in the cerebral infarcti on model produced by the occlusion of the middle cerebral artery in rats and in patients suffering from acute cerebral infarction caused by thromboembolism. In both studies, dapsone displayed a reduction of between 70 and 90 % in the adverse effects which occur as a consequence of the infarction.