发明名称 |
USE OF THE QUINAZOLINE DERIVATIVE ZD6474 COMBINED WITH PLATINUM COMPOUNDS AND OPTIONALLY IONISING RADIATION IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS AND/OR INCREASED VASCULAR PERMEABILITY |
摘要 |
<p>The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of ZD6474 in combination with a platinum anti-tumour agent; to a pharmaceutical composition comprising ZD6474 and a platinum anti-tumour agent; to a combination product comprising ZD6474 and a platinum anti-tumour agent for use in a method of treatment of a human or animal body by therapy; to a kit comprising ZD6474 and a platinum anti-tumour agent; to the use of ZD6474 and a platinum anti-tumour agent in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation.</p> |
申请公布号 |
WO2005004870(A1) |
申请公布日期 |
2005.01.20 |
申请号 |
WO2004GB02932 |
申请日期 |
2004.07.07 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;WEDGE, STEPHEN, ROBERT;RYAN, ANDERSON, JOSEPH |
发明人 |
WEDGE, STEPHEN, ROBERT;RYAN, ANDERSON, JOSEPH |
分类号 |
A61K31/282;A61K31/517;A61K31/555;A61K33/24;A61K41/00;A61P35/00;(IPC1-7):A61K31/517 |
主分类号 |
A61K31/282 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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