发明名称 |
POLYMER-COATED SUBSTRATES FOR IMMOBILIZATION OF BIOMOLECULES AND CELLS |
摘要 |
Methods for preparing a substrate for the arraying and immobilizing of biomolecules or cells are described. The methods include providing a solid support and depositing by a chemical plasma-mediated polymerization process a polymeric coating on the surface. The polymeric coating comprises at least one pendant functional group capable of attaching a biomolecule or a cell. A material of the polymeric coating is preferably selected in such a way that its surface properties enhance binding between the pendant group and the biomolecule or cell. A substrate for the immobilization of biomolecules and cells is also provided. The substrate comprises a solid support made of a polymeric material. The solid support has at least one first pendant functional group suitable for attaching a first biomolecule or a first cell on its surface. The substrate further comprises a polymeric coating deposited on the surface of the substrate. The polymeric coating increases the attachment of the first biomolecule or the first cell to the first functional group. |
申请公布号 |
EP1497302(A2) |
申请公布日期 |
2005.01.19 |
申请号 |
EP20030718448 |
申请日期 |
2003.04.17 |
申请人 |
BECKMAN COULTER, INC. |
发明人 |
MATSON, ROBERT, S. |
分类号 |
B05D7/24;G01N33/543;B01J19/00;C12M1/00;C12M1/40;C12N11/02;C12N15/09;C40B60/14;G01N33/53;G01N33/547;G01N37/00 |
主分类号 |
B05D7/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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