发明名称 |
Immunization by inoculation of DNA transcription unit |
摘要 |
This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune response can provide protection against infection by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.
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申请公布号 |
US6841381(B1) |
申请公布日期 |
2005.01.11 |
申请号 |
US19940187879 |
申请日期 |
1994.01.27 |
申请人 |
UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER;ST. JUDE CHILDREN'S RESEARCH HOSPITAL |
发明人 |
ROBINSON HARRIET L.;FYNAN ELLEN F.;WEBSTER ROBERT G.;LU SHAN |
分类号 |
A61K48/00;A61K9/16;A61K35/76;A61K38/00;A61K39/00;A61K39/145;A61K39/15;A61K39/21;A61P15/16;A61P15/18;A61P31/10;A61P31/12;A61P31/16;A61P33/00;A61P35/00;C07K14/11;C07K14/14;C07K14/155;C07K14/16;C12N15/09;C12N15/44;C12N15/867;C12N15/87;C12R1/91;(IPC1-7):C12N15/63;C12N15/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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