发明名称 |
Syntetiske peptidanaloger af lungeoverfladeproteinet SP-C |
摘要 |
PCT No. PCT/EP95/02028 Sec. 371 Date Nov. 27, 1996 Sec. 102(e) Date Nov. 27, 1996 PCT Filed May 27, 1995 PCT Pub. No. WO95/32992 PCT Pub. Date Dec. 7, 1995Polypeptide analogs of human the human lung surfactant protein, SP-C, are provided. The polypeptides have the following structure: <IMAGE> <IMAGE> <IMAGE> <IMAGE> wherein A is H or Phe, B is Phe or Trp, and C is Ile, Leu, or Ser. They exhibit surfactant activity and are useful in the treatment of respiratory distress syndromes in premature infants and adults. |
申请公布号 |
DK0764172(T3) |
申请公布日期 |
2005.01.10 |
申请号 |
DK19950920906T |
申请日期 |
1995.05.27 |
申请人 |
ALTANA PHARMA AG |
发明人 |
NAVE, RUEDIGER;ULRICH, WOLF-RUEDIGER;STURM, ERNST;HAEFNER, DIETRICH;SCHAEFER, KLAUS, P.;KRUEGER, UWE;MELCHERS, KLAUS |
分类号 |
C12N15/09;A61K9/107;A61K9/127;A61K38/00;A61K38/17;A61K47/24;A61P11/00;A61P11/16;C07K14/785;C12P21/02;C12R1/19;(IPC1-7):C07K14/785 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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