发明名称 |
CD20-SPECIFIC ANTIBODIES AND METHODS OF EMPLOYING SAME |
摘要 |
The present invention provides monoclonal antibodies and antigen-binding fragments thereof that specifically bind to CD20, as well as pharmaceutical compositions comprising the same. The invention further provides methods of using the monoclonal antibodies, antigen-binding fragments, and pharmaceutical compositions, for example, in methods of depleting B cells or in treating B cell disorders. Also provided are cells, nucleic acids and methods for producing the monoclonal antibodies. |
申请公布号 |
WO2005000901(A2) |
申请公布日期 |
2005.01.06 |
申请号 |
WO2004US14326 |
申请日期 |
2004.05.07 |
申请人 |
DUKE UNIVERSITY;TEDDER, THOMAS F.;UCHIDA, JUNJI;HAMAGUCHI, YASUHITO;POE, JONATHAN C. |
发明人 |
TEDDER, THOMAS F.;UCHIDA, JUNJI;HAMAGUCHI, YASUHITO;POE, JONATHAN C. |
分类号 |
C07K16/28;C12N5/20;C12N15/13 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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