发明名称 MEK inhibiting compounds
摘要 This invention provides substituted Phenyl-(2-[1,3,4]thiadiazol-2-yl-phenyl)-amine and (2-[1,3,4]Oxadiazol-2-yl-phenyl)phenyl-amine compounds which act as inhibitors of MAPK/ERK Kinase ("MEK") enzymes and pharmaceutical compositions and methods for their use in immunomodulation and in the treatment and alleviation of inflammation, and proliferative diseases such as cancer and restenosis.
申请公布号 US2005004186(A1) 申请公布日期 2005.01.06
申请号 US20030725206 申请日期 2003.12.01
申请人 PFIZER INC 发明人 BARRETT STEPHEN D.;FLAMME CATHLIN M.;KAUFMAN MICHAEL D.;PLUMMER MARK S.;REED JESSICA E.;WARMUS JOSEPH S.;ZHANG LU-YAN
分类号 A61P29/00;A61P35/00;C07D249/08;C07D249/14;C07D271/10;C07D271/113;C07D285/12;C07D285/135;C07D413/04;C07D413/12;C07D413/14;C07D417/14;(IPC1-7):C07D285/14;C07D271/12;A61K31/433;A61K31/424;A61K31/419 主分类号 A61P29/00
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