发明名称 |
Antigen delivery system and method of production |
摘要 |
The present invention concerns polymer particle vaccine delivery systems in which a water insoluble protein antigen, e.g. a lipidated HpaA protein, is incorporated with particles comprising a polymer matrix. The present invention also concerns a method for incorporating such a water insoluble protein antigen with a polymer matrix in order to produce a polymer particle vaccine delivery system. In addition, the invention also provides a vaccine composition comprising the polymer particle delivery system. The vaccine can be used to treat and/or reduce the risk of for example Helicobacter infection.
|
申请公布号 |
US6838089(B1) |
申请公布日期 |
2005.01.04 |
申请号 |
US19990308435 |
申请日期 |
1999.05.19 |
申请人 |
ASTRAZENECA AB |
发明人 |
CARLSSON HANS;LARSSON ANETTE;SOEDERLIND ERIK |
分类号 |
A61K9/00;A61K9/16;A61K39/00;A61K39/02;A61K39/106;A61K47/24;A61K47/28;A61K47/32;A61K47/34;A61K47/36;A61K47/42;A61P31/04;A61P37/04;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|