| 摘要 |
A novel asymmetric synthesis is provided for preparing optically active amid es of formula (A) and their salts. In the formula, X represents (a) or (b), R represents a mono or bicyclic aryl or heteroaryl group, R is an aryl or heteroaryl radical and R2 and R3 have specified meanings. The products are useful as 5-HT1A antagonist s. Novel diesters useful as intermediates in the process are also disclosed.
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