| 发明名称 |
METHOD OF INHIBITING AMYLOID PROTEIN AGGREGATION AND IMAGING AMYLOID DEPOSITS USING ISOINDOLINE DERIVATIVES |
| 摘要 |
<p>The present invention provides a method of treating Alzheimer's disease using a novel compound of formula (I), wherein X is phenyl or substituted phenyl; Y is phenyl, substituted phenyl, pyridyl, or substituted pyridyl. Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of formula (I) and a method of imaging amyloid deposits using isoindoline derivatives.</p> |
| 申请公布号 |
SI1192131(T1) |
申请公布日期 |
2004.12.31 |
| 申请号 |
SI20000030475T |
申请日期 |
2000.05.31 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
AUGELLI-SZAFRAN CORINNE ELIZABETH;LAI YINGJIE;SAKKAB ANNETTE THERESA;WALKER LARY CRASWELL |
| 分类号 |
A61K31/4035;A61K31/4178;A61K49/06;A61K51/04;A61P25/28;A61P43/00;C07D209/44;C07D401/12;C07D403/12;(IPC1-7):C07D209/44;A61K31/403 |
主分类号 |
A61K31/4035 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
