摘要 |
An ameliorating agent for cancer chemotherapy is disclosed, which comprises a chromanol glucoside represented by the following general formula (1) <CHEM> (wherein R<1>, R<2>, R<3>, and R<4>, which are identical or different from each other, stand for a hydrogen atom or a lower alkyl group, R<5> stands for a hydrogen atom, a lower alkyl group, or a lower acyl group, X stands for a monosaccharide residue or an oligosaccharide residue optionally having the hydrogen atom of the hydroxyl group in the saccharide residue substituted with a lower alkyl group or a lower acyl group, n is an integer in the range of 0 - 6, and m is an integer in the range of 1 - 6). <??>According to this invention, a novel ameliorating agent for cancer chemotherapy is provided which acts safely and effectively in a small dosage to enhance the carcinostatic action of an anti-cancer agent in cancer chemotherapy and repressing side effects by cancer chemotherapy as well.
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申请人 |
KAGIYA, TSUTOMU;CCI CORPORATION |
发明人 |
KAGIYA, TSUTOMU;MURASE, HIRONOBU;KONOVALOVA, NINA PETROVNA;VOLKOVA, LUDMILA MIHAILOVNA;LUGOVSKAYA, NATALIYA YURIEVNA;VASILIEVA, LUBOV SERGEEVNA |