| 发明名称 |
AZEPANE DERIVATIVES AND THEIR USE AS ATK1 INHIBITORS |
| 摘要 |
This invention provides novel azepane derivatives or pharmaceutically acceptable salts thereof, according to the general formula (I) wherein the symbols are defined in the specification, as well as processes for their manufacture. The compounds according to this invention possess anti-cell proliferation activity and show an increased plasma-stability. |
| 申请公布号 |
EP1487819(A2) |
申请公布日期 |
2004.12.22 |
| 申请号 |
EP20030711955 |
申请日期 |
2003.03.10 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
FRIEBE, WALTER-GUNAR;MASJOST, BIRGIT;SCHUMACHER, RALF |
| 分类号 |
A61K31/55;A61P35/00;A61P43/00;C07D223/12;C07D401/12;C07D401/14;C07D403/12;C07D405/14 |
主分类号 |
A61K31/55 |
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