| 发明名称 |
METHOD FOR DIAGNOSING INFLAMMATORY BOWEL DISEASE |
| 摘要 |
<p>The present invention relates to a method for identifying a compound capable of modulating the action of the DLG5 protein which method comprises subjecting one or more test compounds to a screen comprising a polypeptide containing the amino acid sequence shown in SEQ ID NO: 2, or a homologue thereof or a fragment of either. Such compounds may be useful in the treatment of inflammatory bowel disease. The present invention also relates to a method for diagnosing inflammatory bowel disease by detecting variant DLG5.</p> |
| 申请公布号 |
WO2004109288(A1) |
申请公布日期 |
2004.12.16 |
| 申请号 |
WO2004SE00861 |
申请日期 |
2004.06.03 |
| 申请人 |
ASTRAZENECA AB;CORNELIUSSEN, BRIT;SCHREIBER, STEFAN;STOLL, MONIKA |
发明人 |
CORNELIUSSEN, BRIT;SCHREIBER, STEFAN;STOLL, MONIKA |
| 分类号 |
A61K38/17;A61P29/00;C12Q1/68;G01N33/68;(IPC1-7):G01N33/68;G01N33/53;A61K39/395;A61K48/00 |
主分类号 |
A61K38/17 |
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