| 发明名称 |
P53-DEPENDENT NOVEL APOPTOSIS-ASSOCIATED PROTEIN AND METHOD OF SCREENING APOPTOSIS CONTROLLING AGENT |
| 摘要 |
A novel apoptosis-associated gene p53AIPI is isolated by screening for a gene the expression of which is induced by p53. Since the protein encoded by this gene has an activity of inducing apoptosis, this gene is useful in developing effective therapeutic agents for cancer mediated by apoptosis. A method of screening for a compound controlling the induction of apoptosis which is expected as being useful in developing an apoptosis controlling agent. |
| 申请公布号 |
EP1306436(A4) |
申请公布日期 |
2004.12.15 |
| 申请号 |
EP20010956793 |
申请日期 |
2001.08.02 |
| 申请人 |
JAPAN AS REPRESENTED BY THE PRESIDENT OF THE UNIVERSITY OF TOKYO;ONCOTHERAPY SCIENCE, INC. |
发明人 |
NAKAMURA, YUSUKE;ARAKAWA, HIROFUMI |
| 分类号 |
A61K48/00;A61P35/00;A61P43/00;C07K14/47;C12N15/12 |
主分类号 |
A61K48/00 |
| 代理机构 |
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代理人 |
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