发明名称 MODULATION OF IMMUNE RESPONSE BY RIBAVIRIN
摘要 The response of an immune system to a challenge is modified by presenting the system with a nucleoside in a concentration selected to have an effect on a B7 marker that is inverse from the effect of the challenge. Contemplated challenges include allergens, neoplasm, virus, bacteria, infestation, and autoimmune reaction. Molecular markers of particular interest are B7-1 and B7-2. Preferred nucleosides are Ribavirin and Ribavirin analogs, especially provided within a concentration range between about 0.2 :M and about 5 :M, respectively, in a fluid containing cells expressing the B7 marker.
申请公布号 PL364699(A1) 申请公布日期 2004.12.13
申请号 PL19990364699 申请日期 1999.12.20
申请人 ICN PHARMACEUTICALS,INC. 发明人 TAM ROBERT
分类号 A61K31/7084;A61K31/00;A61K31/7052;A61P1/00;A61P1/16;A61P3/10;A61P11/06;A61P15/00;A61P17/06;A61P19/02;A61P21/00;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P37/00;A61P37/02;A61P37/06;A61P37/08 主分类号 A61K31/7084
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