Uses of a thyx polypeptide or a nucleic acid encoding such a polypeptide, in particular for screening anti-bacterial or anti-viral compounds

摘要

The invention is relative to the various uses of a novel enzyme family, referred to as THYX, capable of catalyzing the synthesis of thymidine 5'-monophosphate in the absence of an active thymidylate synthase enzyme (ThyA). The invention also relates to reaction media for the thymidylate synthase activity of a THYX polypeptide as well as screening methods implementing said reaction media, as well as kits for implementing such methods.