发明名称 Heteroarotinoids-anticancer agents with receptor specificity and Tgase activity
摘要 Anticancer compositions having receptor specificity as well as activity in stimulating formation of the enzyme transglutaminase as a marker for anticancer activity. The compositions comprise certain heteroarotinoid structures partially related to trans-retinoic acid through the basic, fused-ring framework.
申请公布号 WO9807716(A3) 申请公布日期 1998.03.26
申请号 WO1997US14720 申请日期 1997.08.21
申请人 THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY 发明人 BERLIN, KENNETH, DARREL;SUBRAMANIAN, SHANKER;NELSON, ELDON, CARL;MADLER, MATORA, MAY;PATTERSON, MANFORD, KENNETH, JR.;BIRCKBICHLER, PAUL, JOSEPH;BENBROOK, DORIS, MANGIARACINA
分类号 C07C69/94;C07D215/48;C07D307/79;C07D311/20;C07D311/58;C07D311/76;C07D317/60;C07D319/18;C07D333/54;C07D335/02;C07D335/06;C07D405/12 主分类号 C07C69/94
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