GENE RECOMBINANT ANIMAL PRODUCING SELENOCYSTEINE-CONTAINING PROTEIN

摘要

PROBLEM TO BE SOLVED: To construct a gene recombinant system for producing a selenocysteine-containing protein in a practically utilizable expression level.

SOLUTION: The gene-recombinant animal capable of expressing the objective selenocysteine-containing protein is created by introducing a gene expression unit having a gene sequence encoding an expression-regulating region actable in the animal individual, a gene sequence encoding the objective selenocysteine-containing protein, and a gene sequence encoding a selenocysteine-inducing sequence (SECIS) into an animal cell, and introducing the resultant animal cell into a mammal or a bird.

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