发明名称 |
Antigens of and antibodies to translocated molecules of microorganisms and uses thereof |
摘要 |
This application describes intracellular, cytoplasmic molecules that are translocated to the surface of a microorganism and participate in binding the microorganism to the surface of a host cell. Examples of such translocated molecules include glycerahdehyde 3-phosphate dehydrogenase, pyruvate dehydrogenase, and elongation factor-Tu. Regions of translocated molecules important for binding, as well as molecules which disrupt binding, are described. Antibodies directed to translocated molecules are also described.
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申请公布号 |
US2004241689(A1) |
申请公布日期 |
2004.12.02 |
申请号 |
US20040485002 |
申请日期 |
2004.06.28 |
申请人 |
BASEMAN JOEL B.;KANNAN THIRUMALAI R.;ALVAREZ RENE |
发明人 |
BASEMAN JOEL B.;KANNAN THIRUMALAI R.;ALVAREZ RENE |
分类号 |
A61K38/00;A61K39/155;C07K14/47;C12N9/02;(IPC1-7):C12Q1/68;A61K39/00;A61K39/38 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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