| 发明名称 |
Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and TACE inhibitors |
| 摘要 |
Compounds of the formulaare useful in treating disease conditions mediated by TNF-alpha, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
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| 申请公布号 |
US6825354(B2) |
申请公布日期 |
2004.11.30 |
| 申请号 |
US20010055502 |
申请日期 |
2001.11.13 |
| 申请人 |
WYETH HOLDINGS CORPORATION |
发明人 |
LEVIN JEREMY I.;VENKATESAN ARANAPAKAM M.;COLE DEREK C.;CHEN JAMES M.;DAVIS JAMIE M.;GROSU GEORGE T. |
| 分类号 |
C07C317/44;C07C317/50;C07C323/60;C07D207/34;C07D209/48;C07D213/56;C07D215/48;C07D215/54;C07D217/26;C07D295/092;C07D309/04;C07D311/84;C07D333/20;C07D333/60;C07D335/02;(IPC1-7):C07D211/72;A61K31/44;A61K31/41 |
主分类号 |
C07C317/44 |
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