发明名称 NEAR INFRARED FLUORESCENT CONTRAST AGENT AND METHOD FOR FLUORESCENCE IMAGING
摘要 A near infrared fluorescent contrast agent which is excellent in permeability in a living tissue and enables specific imaging of tumor and/or blood vessel, comprising a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R7, and R8 represent a C1-C10 alkyl group or the like; R3, R4, R5, R6, R9, R10, R11, and R12 represent a hydrogen atom, a C1-C6 alkyl group, an aryl group or the like; X1 and X2 represent a C1-C15 alkyl group or an aryl group and X1 and X2 in total have 0 to 4 carboxyl groups; m1, m2, and m3 represents 0 or 1; L1 to L7 independently represent a methine group; M represents a hydrogen atom, a metal, or a quaternary ammonium salt; and n represents an integer of 1 to 7 necessary for neutralizing charge.
申请公布号 KR20040099301(A) 申请公布日期 2004.11.26
申请号 KR20047013937 申请日期 2003.03.07
申请人 发明人
分类号 A61K49/00;C07D409/14;A61B1/00;A61B3/10;A61B3/14;C07D209/14;C07D209/60;G01N21/64 主分类号 A61K49/00
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