发明名称 |
IDENTIFICATION OF CLONAL CELLS BY REPEATS IN (EG.) T-CELL RECEPTOR V/D/J GENES |
摘要 |
<p>The present invention relates to a method of characterising a nucleic acid region and, more particularly, to a method of analysing a marker nucleic acid region. The method of the present invention is based on identification of one or both of the nucleic acid regions flanking a marker nucleic acid region and provides a means of analysing a marker nucleic acid region which is characteristic of a clonal population of cells. The method of the present invention is useful in the context of enabling a range of applications including, but not limited to, monitoring the progression of a condition characterised by the presence of a clonal populations of cells (such as a neoplastic condition), monitoring the levels of one or more clonal cell population, predicting the likelihood of a subject's relapse from a remissive state to a disease state, for assessing the effectiveness of existing therapeutic drugs and/or new therapeutic agents and identifying the presence of a marker region.</p> |
申请公布号 |
WO2004101815(A1) |
申请公布日期 |
2004.11.25 |
申请号 |
WO2004AU00625 |
申请日期 |
2004.05.13 |
申请人 |
MONOQUANT PTY LTD;MORLEY, ALEXANDER, ALAN;BRISCO, MICHAEL;SYKES, PAMELA |
发明人 |
MORLEY, ALEXANDER, ALAN;BRISCO, MICHAEL;SYKES, PAMELA |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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