发明名称 IDENTIFICATION OF CLONAL CELLS BY REPEATS IN (EG.) T-CELL RECEPTOR V/D/J GENES
摘要 <p>The present invention relates to a method of characterising a nucleic acid region and, more particularly, to a method of analysing a marker nucleic acid region. The method of the present invention is based on identification of one or both of the nucleic acid regions flanking a marker nucleic acid region and provides a means of analysing a marker nucleic acid region which is characteristic of a clonal population of cells. The method of the present invention is useful in the context of enabling a range of applications including, but not limited to, monitoring the progression of a condition characterised by the presence of a clonal populations of cells (such as a neoplastic condition), monitoring the levels of one or more clonal cell population, predicting the likelihood of a subject's relapse from a remissive state to a disease state, for assessing the effectiveness of existing therapeutic drugs and/or new therapeutic agents and identifying the presence of a marker region.</p>
申请公布号 WO2004101815(A1) 申请公布日期 2004.11.25
申请号 WO2004AU00625 申请日期 2004.05.13
申请人 MONOQUANT PTY LTD;MORLEY, ALEXANDER, ALAN;BRISCO, MICHAEL;SYKES, PAMELA 发明人 MORLEY, ALEXANDER, ALAN;BRISCO, MICHAEL;SYKES, PAMELA
分类号 C12Q1/68;(IPC1-7):C12Q1/68 主分类号 C12Q1/68
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