| 摘要 |
<p>Novel anti-IL-23p40 specific human Ig derived proteins, including, without limitation, antibodies, fusion proteins, and mimetibodies, isolated nucleic acids that encode the anti-IL-23p40 Ig derived proteins, vectors, host cells , transgenic animals or plants, and methods of making and using thereof, are useful for therapeutic compositions, methods and devices. Preferably, the an ti- IL-23p40 specific human Ig derived proteins do not bind the p40 subunit of I L- 12 and, thus, do not neutralize IL-12-related activity.</p> |
