| 发明名称 |
2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS |
| 摘要 |
This invention relates to 8-aza prostanoid analogs which are generally EP4 receptor agonists and are represented by Formula I:wherein Q, B, X, I, Z, A and R1-R6 are as defined in the description, their synthesis and use for treatment of osteoporosis and increasing bone density.
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| 申请公布号 |
CA2451393(A1) |
申请公布日期 |
2003.01.30 |
| 申请号 |
CA20022451393 |
申请日期 |
2002.07.11 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ELWORTHY, TODD RICHARD;ROEPEL, MICHAEL GARRET;SMITH, DAVID BERNARD |
| 分类号 |
C07D207/20;A61K31/4015;A61P19/00;A61P19/10;C07D207/26;C07D207/273;C07D207/46;C07D405/06;(IPC1-7):A61K31/401;C07D207/12 |
主分类号 |
C07D207/20 |
| 代理机构 |
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