发明名称 |
GENE SILENCING BY SYSTEMIC RNA INTERFERENCE |
摘要 |
Nucleic acid and protein sequences relating to a gene required for systemic RNAi are disclosed. The SID-1 and 2 proteins are shown to be required for systemic RNAi. Nucleic acids, vectors, transformed cells, transgenic animals, polypeptides, and antibodies relating to the sid-1 and 2 genes and proteins are disclosed. Also provided are methods for reducing the expression of a target gene in a cell, a population of cells, or an animal. |
申请公布号 |
WO2004099386(A2) |
申请公布日期 |
2004.11.18 |
申请号 |
WO2004US13956 |
申请日期 |
2004.05.05 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;HUNTER, CRAIG, P.;WINSTON, WILLIAM;FEINBERG, EVAN |
发明人 |
HUNTER, CRAIG, P.;WINSTON, WILLIAM;FEINBERG, EVAN |
分类号 |
C07K14/705 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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