摘要 |
PROBLEM TO BE SOLVED: To obtain a new prophylactic/therapeutic agent for diseases caused by the proliferation of vascular smooth muscle, e.g. reobstruction occurring after the treatment by expanding a balloon a cardiac coronary artery obstruction. SOLUTION: The new prophylactic/therapeutic agent is an inhibitor for the proliferation of vascular smooth muscle, comprising as active ingredient a 14-membered macrolide compound, specifically erythromycin or its derivative, roxithromycin or its derivative, or being a cycline-dependent kinase conjugate expression enhancer. A method for treating the diseases caused by the proliferation of vascular smooth muscle is also provided. COPYRIGHT: (C)2005,JPO&NCIPI
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