发明名称 |
MODIFIED TRANSFERIN-ANTIBODY FUSION PROTEINS |
摘要 |
Modified fusion proteins of transferrin and therapeutic proteins or peptides, preferably antibody variable regions, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor. |
申请公布号 |
WO2004020404(A3) |
申请公布日期 |
2004.11.11 |
申请号 |
WO2003US26744 |
申请日期 |
2003.08.28 |
申请人 |
BIOREXIS PHARMACEUTICAL CORPORATION;SADEGHI, HOMAYOUN;PRIOR, CHRISTOPHER, P.;TURNER, ANDREW |
发明人 |
SADEGHI, HOMAYOUN;PRIOR, CHRISTOPHER, P.;TURNER, ANDREW |
分类号 |
A01K67/00;A61K38/00;A61K39/395;A61K47/48;C07D;C07H21/04;C07K14/79;C07K16/00;C07K16/24;C07K19/00;C12N15/12;C12N15/13;C12N15/62;C12N15/63;C12N15/65;C12N15/86 |
主分类号 |
A01K67/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|