发明名称 INHIBITORS OF AKT ACTIVITY
摘要 The present invention is directed to compounds which contain a substituted pyridine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
申请公布号 WO2004096135(A2) 申请公布日期 2004.11.11
申请号 WO2004US12265 申请日期 2004.04.20
申请人 MERCK & CO., INC.;DUGGAN, MARK, E.;LINDSLEY, CRAIG, W.;WU, ZHICAI;ZHAO, ZHIJIAN;HARTNETT, JOHN, C. 发明人 DUGGAN, MARK, E.;LINDSLEY, CRAIG, W.;WU, ZHICAI;ZHAO, ZHIJIAN;HARTNETT, JOHN, C.
分类号 A61K;A61K31/44;C07D213/02;C07D213/85;C07D401/04;C07D401/12;C07D401/14;C07D413/12;C07D417/04;C07D417/12;C07D417/14 主分类号 A61K
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