A method of transducing a neural stem cell with a nucleic acid target sequence is disclosed. The method comprises providing a binding medium comprising at least a fragment of fibronectin. A viral vector containing the target sequence is then added to the binding medium such that the viral vector binds to the fragment. The cell is added to the binding medium such that the cell is bound to the fragment. The cell is then transduced with the target sequence.
申请公布号
WO2004097025(A2)
申请公布日期
2004.11.11
申请号
WO2004EP04619
申请日期
2004.04.30
申请人
THE NORWEGIAN RADIUM HOSPITAL RESEARCH FOUNDATION;FODSTAD, OEYSTEIN;RAPPA, GERMANA;LORICO, AURELIO;KRAUSS, STAFAN, JOHANNES, KARL
发明人
FODSTAD, OEYSTEIN;RAPPA, GERMANA;LORICO, AURELIO;KRAUSS, STAFAN, JOHANNES, KARL