发明名称 Aza spiro alkane derivatives as inhibitors of metallproteases
摘要 The present invention provides a compound of Formula (I) or Formula (II): enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
申请公布号 AU2004233863(A1) 申请公布日期 2004.11.11
申请号 AU20040233863 申请日期 2004.04.23
申请人 INCYTE CORPORATION 发明人 FENGLEI ZHANG;JINCONG ZHOU;WENQING YAO;MEIZHONG XU;BRIAN METCALF
分类号 A61K;A61K31/4188;A61K31/424;A61K31/428;A61K31/4747;C07D;C07D471/10;C07D491/10;C07D497/10 主分类号 A61K
代理机构 代理人
主权项
地址