发明名称 |
Purification process of N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethyl-acetamide (zaleplon) and zaleplon crystalline forms prepared in such a manner |
摘要 |
<p>Zaleplon can be separated from a regioisomer impurity by crystallization from selected solvents or by adding an anti-solvent to a solution of zaleplon and the regioisomer. Zaleplon crystalline Forms II, III, IV, and V are useful for the treatment of insomnia. These crystalline Forms are described along with processes for making them v crystallize from selected solvents.</p> |
申请公布号 |
CZ20040071(A3) |
申请公布日期 |
2004.11.10 |
申请号 |
CZ20040000071 |
申请日期 |
2002.08.01 |
申请人 |
BIOGAL GYOGYSZERGYAR RT |
发明人 |
FEHER ERIKA;KORODI FERENC;SINGER CLAUDE;MAGYAR ERIKA |
分类号 |
A61K;A61P25/20;C07D487/04;(IPC1-7):C07D487/04;A61K31/519 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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