发明名称 |
Gene expression base sequences for therapeutic use and drugs for gene therapy |
摘要 |
The base sequence for the expression of a therapeutic gene and the medicament for gene therapy are disclosed. There is also disclosed the base sequence for the expression of a therapeutic gene, said sequence being shown in any one of from (a) to (d) and capable of directing the expression of the therapeutic gene specifically to squamous epithelium:(a) the base sequence set forth in SEQ ID NO:1 in the Sequence Listing;(b) the base sequence set forth in SEQ ID NO:18 in the Sequence Listing;(c) the base sequence set forth in SEQ ID NO:17 in the Sequence Listing; and(d) the base sequence set forth in SEQ ID NO:16 in the Sequence Listing.Moreover, there is disclosed the medicament for gene therapy containing a therapeutic gene downstream any of the above-mentioned base sequences, capable of directing the expression of the therapeutic gene specifically to squamous epithelium.
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申请公布号 |
US6815430(B1) |
申请公布日期 |
2004.11.09 |
申请号 |
US20020958021 |
申请日期 |
2002.01.07 |
申请人 |
HISAMITSU PHARMACEUTICAL CO., INC. |
发明人 |
YUDA KAZUHIRO;AKIYAMA KATSUHIKO;GOTO TAKESHI;HAMADA KATSUYUKI |
分类号 |
A61K38/00;A61K48/00;C07K14/47;C12N15/63;(IPC1-7):C07H21/04;A01N43/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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