发明名称 |
Therapeutic inhibitor of vascular smooth muscle cells |
摘要 |
Methods are provided for inhibiting stenosis following vascular trauma or disease in a mammalian host, comprising administering to the host a therapeutically effective dosage of a therapeutic conjugate containing a vascular smooth muscle binding protein that associates in a specific manner with a cell surface of the vascular smooth muscle cell, coupled to a therapeutic agent dosage form that inhibits a cellular activity of the muscle cell. Methods are also provided for the direct and/or targeted delivery of therapeutic agents to vascular smooth muscle cells that cause a dilation and fixation of the vascular lumen by inhibiting smooth muscle cell contraction, thereby constituting a biological stent.
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申请公布号 |
US2004219223(A1) |
申请公布日期 |
2004.11.04 |
申请号 |
US20040860486 |
申请日期 |
2004.06.02 |
申请人 |
SCIMED LIFE SYSTEMS, INC. |
发明人 |
KUNZ LAWRENCE L. |
分类号 |
A61K47/48;(IPC1-7):A61K9/14;A61F2/06 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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