发明名称 Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
摘要 A novel method of treating and preventing diseases is provided. In particular, compositions and methods of blocking diseases associated with aberrant levels of nitric oxide and facilitated by a serine proteolytic (SP) activity are disclosed, which consist of administering to a subject a therapeutically effective amount of a compound having a serine protease inhibitory activity. Among effective compounds are alpha1-antitrypsin and synthetic drugs mimicking some or all of the actions of alpha1-antitrypsin.
申请公布号 US2004220242(A1) 申请公布日期 2004.11.04
申请号 US20030427929 申请日期 2003.05.02
申请人 SHAPIRO LELAND 发明人 SHAPIRO LELAND
分类号 A61K31/00;A61K31/4245;A61K38/57;(IPC1-7):A61K31/424 主分类号 A61K31/00
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