发明名称 |
METHOD OF ACCUMULATING ALLERGEN-SPECIFIC T CELL ANTIGEN DETERMINANT IN PLANT AND PLANT HAVING THE ANTIGEN DETERMINANT ACCUMULATED THEREIN |
摘要 |
As techniques of accumulating a human T cell epitope in rice albumen, a meth od comprising accumulating a T cell epitope-attached peptide (7crp) directly in seeds, and a method comprising inserting 7crp into the variable region of glutelin, which is a major storage protein of rice, and expressing and accumulating the same as a part of the glutelin storage protein are develope d. It is strongly expected that the rice capable of producing the T cell epitop e- attached peptide thus developed would serve as a practically usable edible vaccine against cedar pollen allergy. |
申请公布号 |
CA2523459(A1) |
申请公布日期 |
2004.11.04 |
申请号 |
CA20042523459 |
申请日期 |
2004.04.23 |
申请人 |
NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES |
发明人 |
TAKAGI, HIDENORI;TAKAIWA, FUMIO |
分类号 |
A01H5/00;A23L1/10;A23L1/182;A23L1/212;A23L1/305;A61K36/899;A61K38/56;A61K39/35;A61K39/36;A61P37/08;C07K14/415;C12N5/10;C12N15/09;C12N15/11;C12N15/82 |
主分类号 |
A01H5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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