发明名称 |
MOUSE WITH DEFICIENCY OF GLUTAMATE TRASNPORTER GLAST FUNCTION |
摘要 |
<p>It is intended to provide a GLAST knockout mouse lacking the function of endogenous glutamate transporter GLAST gene which shows: 1) an ocular tension within the normal range; and 2) a decrease in retinal ganglion cell count compared with a normal wild type mouse. Owing to the ocular properties, this knockout mouse is useful as a normal tension glaucoma model. By using this knockout mouse, a compound useful in treating normal tension glaucoma can be screened.</p> |
申请公布号 |
WO2004092371(A1) |
申请公布日期 |
2004.10.28 |
申请号 |
WO2004JP05253 |
申请日期 |
2004.04.13 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY;TANAKA, KOHICHI;HARADA, TAKAYUKI |
发明人 |
TANAKA, KOHICHI;HARADA, TAKAYUKI |
分类号 |
A01K67/027;C12N15/85;(IPC1-7):C12N15/09;G01N33/50;G01N33/15 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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