发明名称 |
Novel method for identifying antibacterial compounds |
摘要 |
The present invention relates to a method for identifying an antagonist or inhibitor of the expression of a gene encoding a polypeptide essential for bacterial growth or survival as well as for an antagonist or inhibitor of said polypeptide. The invention further relates to a method for improved antagonists or inhibitors. The invention also provides an antagonist or inhibitor of the activity of said polypeptide. The invention is further related to a method for producing a therapeutic agent in a composition comprising said antagonist or inhibitor. Furthermore, the invention is related to the use of the polypeptide and the antagonist or inhibitor as well as to a method to identify a surrogate marker. |
申请公布号 |
AU777774(B2) |
申请公布日期 |
2004.10.28 |
申请号 |
AU20000041167 |
申请日期 |
2000.04.07 |
申请人 |
GPC BIOTECH AG |
发明人 |
HANNES LOFERER;ALEXANDER JACOBI;ANDREI GRIGORIEV |
分类号 |
G01N33/50;A61K38/00;A61K45/00;A61P31/04;C07K14/245;C12N15/09;C12Q1/02;C12Q1/18;C12Q1/68;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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