METHODS AND DE VICES FOR EPITHELIAL PROTECTION DURING PHOTODYNAMIC THERAPY
摘要
<p>Methods for preventing damage to the epidermis during PDT induced using a pre-photosensitizing agent are provided. The methods of the present invention utilize spatial confinement to control formation of a photoactive species from a topicallyapplied pre-photosensitizing agent. In one embodiment, thermal inhibition is used to prevent the metabolism of a pre-photosensitizing agent in epithelial tissue surrounding a treatment site. In another embodiment, a chemical inhibitor can be applied to the epithelial tissue to inhibit the conversion of a pre-photosensitizing agent into a phototoxic species.</p>
申请公布号
WO2004091629(A1)
申请公布日期
2004.10.28
申请号
WO2004US11585
申请日期
2004.04.15
申请人
THE GENERAL HOSPITAL CORPORATION;ANDERSON, RICHARD, ROX;ORTEL, BERNARD;BATTLE, ELIOT;JOE, EDWIN