发明名称 |
ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS |
摘要 |
A method to enhance the cytotoxic activity of an antineoplastic drug comprising administering an effective amount of the antineoplastic drug to a host exhibiting abnormal cell proliferation in combination with an effective cytotoxicity-increasing amount of an antioxidant. The invention also includes a method to decrease the toxicity to an antineoplast ic agent or increase the therapeutic index of an antineoplastic agent administered for the treatment of a solid growth of abnormally proliferating cells, comprising administering an antioxidant prior to, with, or following the antineoplastic treatment.
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申请公布号 |
CA2294247(C) |
申请公布日期 |
2004.10.26 |
申请号 |
CA19982294247 |
申请日期 |
1998.07.01 |
申请人 |
ATHEROGENICS, INC. |
发明人 |
BEAUCHAMP, R. DANIEL;MEDFORD, RUSSELL M.;COFFEY, ROBERT J.;CHINERY, REBECCA;WADZINSKI, BRIAN |
分类号 |
A61K47/20;A61K31/00;A61K31/138;A61K31/198;A61K31/336;A61K31/337;A61K31/34;A61K31/357;A61K31/365;A61K31/381;A61K31/395;A61K31/396;A61K31/40;A61K31/407;A61K31/409;A61K31/416;A61K31/4164;A61K31/4166;A61K31/4168;A61K31/4178;A61K31/4188;A61K31/4196;A61K31/4353;A61K31/437;A61K31/4375;A61K31/4468;A61K31/451;A61K31/47;A61K31/4704;A61K31/473;A61K31/495;A61K31/5025;A61K31/506;A61K31/513;A61K31/519;A61K31/52;A61K31/53;A61K31/566;A61K31/585;A61K31/67;A61K31/675;A61K31/70;A61K31/7008;A61K31/704;A61K31/7042;A61K31/706;A61K31/7064;A61K31/7072;A61K31/7076;A61K31/7135;A61K38/43;A61K38/45;A61K38/55;A61K45/00;A61K45/06;A61P9/00;A61P17/06;A61P35/00;A61P43/00;(IPC1-7):A61K31/00 |
主分类号 |
A61K47/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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