摘要 |
<p>The invention relates to the use of extracts containing phytoestrogen, which selectively exhibit an estrogen-receptor-beta modulating effect without producing an uterotropic reactio. In the treatment of clinical characteristics and pathophysiological conditions, which are selected from the groups containing: obesity and possible influences of the metabolic syndrome, especially hypertonia, arteriosclerosis, heart attacks, hyperandrogenamisis; menopausal continence troubles; menopausal hot flushes, which are associated with hyperstimulation of the hypothalamic gonadotropine releasing hormone- pulse generator; disturbed steroid hormone synthesis, especially the progesterone synthesis of the human Corpus luteum as a cause of luteal insufficiency; Alzheimer's disease, which is associated with an increased expression of the estrogen-receptor - beta in hippocampal neurones.</p> |