Chiral binaphthyl diphenyl phosphines and their complexes with transition metals, useful as catalysts for asymmetric reductions

摘要

Chiral diphosphine derivatives of formula (I) in racemic or optically active forms. Chiral diphosphine derivatives of formula (I) in racemic or optically active forms. [Image] R1, R2H or a substituent; Ar1, Ar2alkyl, alkenyl, cycloalkyl, aryl, or arylalkyl; X1, X2H or a water-soluble group selected from ammonium, guanidinium, polyoxy alkalkylenated amino or carboxylate, no more than one of X1 and X2 being H Independent claims are included for (1) complexes of (I) with a transition metal, especially Rh, Ru, Re, Ir, Co, Ni, Pt, or Pd, (2) for the use of such complexes for the asymmetric hydrogenation of C=O and C=C bonds, and (3) for the use of the racemic chiral diphosphines with a chiral diamine, especially 1,2-diamino-1,2-diphenylethane for the selective reduction of ketones.