发明名称 PREVENTION AND TREATMENT OF ALZHEIMER AMYLOID DEPOSITION
摘要 The present invention is directed to a method of preventing or treating Alzheimer's Disease or of inhibiting accumulation of amyloid-j3 deposits in a subject by administering to the subject an agent which inhibits interaction between amyloid-beta and proteins which chaperone amyloid-beta under conditions effective to prevent or treat Alzheimer's Disease in the subject or to inhibit accumulation of amyloid-beta deposits in the subject's brain, respectively. Another embodiment of the present invention relates to a method of inhibiting interaction between apolipoprotein E and amyloid-beta by administering an agent which blocks interaction of apolipoprotein E and amyloid-(beta under conditions effect to block such interaction.
申请公布号 WO2004087733(A2) 申请公布日期 2004.10.14
申请号 WO2004US09045 申请日期 2004.03.26
申请人 NEW YORK UNIVERSITY 发明人 WISNIEWSKI, THOMAS;SADOWSKI, MARCIN;SIGURDSSON, EINAR, M.
分类号 A61K38/17;C07K 主分类号 A61K38/17
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