发明名称 Uniform molecular weight polymers
摘要 A polymer comprising the unit (I) wherein R is selected form the group consisting of hydrogen, C1-C18 alkyl, C1-C18 aralkyl, C1-C18 alkaryl, carboxylic acid, carboxy-C1-6alkyl, or any one of the C1-C18 alkyl, C1-C18 alkenyl, C1-C18 aralkyl, C1-C18 alkaryl substituted with a heteroatom within, or attached to, the carbon backbone; R<1 >is selected from the group consisting of hydrogen, C1-C6 alkyl groups; X is an acylating agent and wherein the polymer has a polydispersity of less than 1.4, preferably less than 1.2 and a molecular weight (Mw) of less than 100,000, the polymer is preferably made by controlled radical polymerization and is useful in the production of polymer drug conjugates with desirable biological profiles.
申请公布号 US6803438(B1) 申请公布日期 2004.10.12
申请号 US20020070318 申请日期 2002.08.09
申请人 POLYTHERICS LIMITED 发明人 BROCCHINI STEPHEN JAMES;GODWIN ANTONY
分类号 A61K47/48;C08F20/10;C08F20/30;C08F20/34;C08F20/36;C08F120/10;C08F220/10;C08F246/00;(IPC1-7):C08F18/00 主分类号 A61K47/48
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