发明名称 |
Composition for inducing islet neogenesis, containing gastrin/CCK receptor ligands and EGF receptor ligands. |
摘要 |
Compositions and methods are provided for achieving in vivo islet cell regeneration in subjects with preexisting diabetes. The methods comprise short term treatment with a composition having a gastrin/cholecystokinin receptor ligand and an EGF receptor ligand. Treatment with such a composition for a short term resulted in a prolonged period of increased insulin release, decreased fasting blood glucose, and improved glucose tolerance, the prolonged efficacy, the period being considered from the time of cessation of treatment. |
申请公布号 |
ZA200305347(B) |
申请公布日期 |
2004.10.11 |
申请号 |
ZA20030005347 |
申请日期 |
2003.07.10 |
申请人 |
WARATAH PHARMACEUTICALS, INC. |
发明人 |
STEPHEN J. BRAND |
分类号 |
A61K38/22;A61K38/27;A61K38/28;A61K45/06;A61P3/10;A61P43/00 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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