THE COLON-TARGETED PHARMACEUTICAL COMPOSITIONS OF GASTROINTESTINAL MOTILITY DRUGS AND THEIR USE

摘要

The invention relates to, the colon-targeted pharmaceutical compositions of gastrointestinal motility drugs and their use. The compositions consist of the colon-targeted materials and the unit dose that comprising clinical effective amount of gastrointestinal motility drugs and the pharmaceutical acceptable excipients. The said colon-targeted materials may be the outer coating surrounding the unit dose or capsules that can solve in the colon. It is experimentally demonstrated that the colon-targeted composition according to, the invention is significant superior to, the common formulation and the drugs that are usually used to, treat constipation clinically.