发明名称 |
NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS I FOR TREATING HIV MEDIATED DISEASES |
摘要 |
This invention relates to novel heterocyclic compounds of formula (I) wherei n R1- R4, X1 and X2 are as defined in the summary and pharmaceutically acceptable salts and solvates thereof, methods to inhibit or modulate Human Immunodeficiency Virus (HIV) reverse transcriptase with compounds of formula (I), pharmaceutical compositions containing of formula (I) admixed with at least one solvent, carrier or excipient and processes to prepare compounds o f formula (I). The compounds are useful for treating disorders in which HIV an d genetically related viruses are to implicated.
|
申请公布号 |
CA2518437(A1) |
申请公布日期 |
2004.10.07 |
申请号 |
CA20042518437 |
申请日期 |
2004.03.22 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
SWEENEY, ZACHARY KEVIN;DUNN, JAMES PATRICK;SWALLOW, STEVEN |
分类号 |
A61P31/18;C07D249/12;C07D271/10;C07D271/113;C07D285/12;C07D285/13;(IPC1-7):C07D249/12;A61K31/419;A61K31/424;A61K31/433 |
主分类号 |
A61P31/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|